free radical

noun

: an especially reactive atom or group of atoms that has one or more unpaired electrons
especially : one that is produced in the body by natural biological processes or introduced from an outside source (such as tobacco smoke, toxins, or pollutants) and that can damage cells, proteins, and DNA by altering their chemical structure

Examples of free radical in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Antioxidants are compounds that protect cells and tissues from damaging molecules (free radicals). Amy Brownstein, Verywell Health, 15 June 2026 Staying true to its South Asian roots, key ingredients include amla fruit extract (more commonly known as Indian gooseberry oil), which is rich in vitamin C to brighten bouts of hyperpigmentation and protect skin against free radicals (which can fast-track signs of aging). Jailynn Taylor, Allure, 13 June 2026 This matters because antioxidants can help protect healthy cells from free radicals, or harmful molecules that cause damage. Kirsten Nunez, Martha Stewart, 13 June 2026 Better Heart Health Green tea contains antioxidants like polyphenols and catechins, which reduce harmful compounds called free radicals in the body. Trista Chan, Health, 10 June 2026 See All Example Sentences for free radical

Word History

First Known Use

1870, in the meaning defined above

Time Traveler
The first known use of free radical was in 1870

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Cite this Entry

“Free radical.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/free%20radical. Accessed 24 Jun. 2026.

Medical Definition

free radical

noun
: an especially reactive atom or group of atoms that has one or more unpaired electrons
especially : one that is produced in the body by natural biological processes or introduced from outside (as in tobacco smoke, toxins, or pollutants) and that can damage cells, proteins, and DNA by altering their chemical structure

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